Make a statement--and support a worthy cause--with this limited-edition Key to the Cure cotton jersey t-shirt available now at Saks Fifth Avenue.

The long sleeve shirt, designed by Donna Karan exclusively for Saks and modeled by Uma Thurman, will benefit women's breast cancer research. The shirt sells for $35.

Through tee shirt sales at Saks Fifth Avenue New York, Saks

Fifth Avenue OFF 5TH stores, www.saks.com and a four-day shopping weekend October 21-24, the company will donate $375,000 to the Breast Cancer Research Foundation.

--Dana Wilson